Choline

Origin of Ingredient

found in eggs, meat and legumes; supplement material is manufactured

History of Ingredient

Choline moved from food, biochemical or specialist use into modern supplements as purification, fermentation, extraction and standardisation technologies developed.

Scientific Makeup of Ingredient

precursor to phosphatidylcholine and acetylcholine; methyl-group metabolism via betaine

UK Legal Claim

• Choline contributes to normal homocysteine metabolism.
• Choline contributes to normal lipid metabolism.
• Choline contributes to the maintenance of normal liver function. Conditions: Check applicable source-level conditions and finished-product composition before use.

EU Legal Claim

• Choline contributes to normal homocysteine metabolism.
• Choline contributes to normal lipid metabolism.
• Choline contributes to the maintenance of normal liver function. Conditions: Check applicable source-level conditions and finished-product composition before use.

US Legal Claim

FDA does not pre-approve ordinary dietary-supplement structure/function claims. Example for regulatory review only (NOT FDA-approved wording): “Supports normal cognitive/brain function.” The marketer must hold substantiation, avoid disease claims, use the DSHEA disclaimer and notify FDA within 30 days after first marketing.

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August 24, 2024

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